Efficiency of Artificial Intelligence for Interpretation of Chest Radiograms in the Republic of Tajikistan

Main Article Content

Bobokhojaev OI
Abdulloev NN
Khushvakhtov ShD
Shukurov SG

Abstract

The article presents data from recent publications and own data on screening studies with interpretation of chest radiographs using artificial intelligence CAD (Computer-Assisted Diagnosis), which, according to WHO recommendations, provides more accurate clinical thresholds for deciding who needs to take a sputum test. Another aspect of the WHO recommendations is the cost-effectiveness of CAD as a tool for triaging patients with tuberculosis symptoms in low-income countries with a high incidence of tuberculosis. Compared with smear microscopy and GeneXpert, without preliminary sorting, the use of mobile digital X-ray machines equipped with a CAD tool reduces costs, allowing sorting of individuals suspected of having tuberculosis for testing on GeneXpert, while reducing the time to start tuberculosis treatment.


Thus, conducting a study using portable X-ray machines using a CAD program is a low-cost and easy-to-implement method, does not require large funds, does not require separate rooms, is highly effective, has good image quality, allows you to quickly clarify individuals suspected of having tuberculosis, differentiating it from other pathological changes in the lungs.


Our experience shows that machine analysis of chest computed tomography data, due to the higher resolution capabilities of the method and the absence of fundamental disadvantages of radiography, including the effect of shadow summation, the presence of “blind” zones, etc., is finding increasing application in both diagnostics and screening of respiratory diseases. Our use of this tool allowed us to identify additional new cases of phthisio-onco-pulmonary diseases in field conditions.

Article Details

OI, B., NN, A., ShD, K., & SG, S. (2024). Efficiency of Artificial Intelligence for Interpretation of Chest Radiograms in the Republic of Tajikistan. Journal of Pulmonology and Respiratory Research, 8(2), 069–073. https://doi.org/10.29328/journal.jprr.1001064
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Copyright (c) 2024 Bobokhojaev OI, et al.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

World Health Organization. Global TB Report 2022. WHO; 2022. Available from: https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2022

Bobokhojaev OI. Experience in optimizing the accessibility of services for tuberculosis in the Republic of Tajikistan. J Community Med Health Solut. 2022;3:064-068. Available from: https://doi.org/10.29328/journal.jcmhs.1001022

Bobokhojaev OI. Long term results of 10 years of observation of cured cases of pulmonary tuberculosis. J Pulmonol Respir Res. 2022;6:007-011. Available from: https://doi.org/10.29328/journal.jprr.1001036

World Health Organization. Chest radiography in tuberculosis detection – summary of current WHO recommendations and guidance on programmatic approaches. WHO; 2016. Available from: https://www.who.int/publications/i/item/9789241511506

Adams SJ, Henderson RDE, Yi X, Babyn P. Artificial intelligence solutions for analysis of X-ray images. Can Assoc Radiol J. 2021 Feb;72(1):60-72. Available from: https://doi.org/10.1177/0846537120941671

Khan AI, Shah JL, Bhat MM. CoroNet: A deep neural network for detection and diagnosis of COVID-19 from chest x-ray images. Comput Methods Programs Biomed. 2020;196:105581. Available from: https://doi.org/10.1016/j.cmpb.2020.105581

Apostolopoulos ID, Mpesiana TA. COVID-19: automatic detection from X-ray images utilizing transfer learning with convolutional neural networks. Phys Eng Sci Med. 2020;43:635-640. Available from: https://doi.org/10.1007/s13246-020-00865-4

Ather S, Kadir T, Gleeson F. Artificial intelligence and radiomics in pulmonary nodule management: current status and future applications. Clin Radiol. 2020;75(1):13-19. Available from: https://doi.org/10.1016/j.crad.2019.04.017

Behzadi-Khormouji H, Rostami H, Salehi S, Derakhshande-Rishehri T, Masoumi M, Salemi S, et al. Deep learning, reusable and problem-based architectures for detection of consolidation on chest X-ray images. Comput Methods Programs Biomed. 2020;185:105162. Available from: https://doi.org/10.1016/j.cmpb.2019.105162

Chassagnon G, Vakalopoulou M, Paragios N, Revel MP. Artificial intelligence applications for thoracic imaging. Eur J Radiol. 2020;23:108774. Available from: https://doi.org/10.1016/j.ejrad.2019.108774

CAD and X-ray training modules. Stop TB Partnership. 2022. Available from: https://www.stoptb.org/resources-implementing-cad-and-xray/cad-and-x-ray-training-modules

Bashir S, Kik SV, Ruhwald M, Khan A, Tariq M, Hussain H, et al. Economic analysis of different throughput scenarios and implementation strategies of computer-aided detection software as a screening and triage test for pulmonary TB. PLoS One. 2022;17(12):e0277393. Available from: https://doi.org/10.1371/journal.pone.0277393

Dvijotham KD, Winkens J, Barsbey M, Ghaisas S, Stanforth R, Pawlowski N, et al. Enhancing the reliability and accuracy of AI-enabled diagnosis via complementarity-driven deferral to clinicians. Nat Med. 2023;29(7):1814-1820. Available from: https://doi.org/10.1038/s41591-023-02437-x

Dohal M, Porvaznik I, Solovic I, Mokry J. Advancing tuberculosis management: the role of predictive, preventive, and personalized medicine. Front Microbiol. 2023;14:1225438. Available from: https://doi.org/10.3389/fmicb.2023.1225438

Hwang EJ, Goo JM, Nam JG, Park CM, Hong KJ, et al. Conventional versus artificial intelligence-assisted interpretation of chest radiographs in patients with acute respiratory symptoms in the emergency department: A pragmatic randomized clinical trial. Korean J Radiol. 2023;24(3):259-270. Available from: https://doi.org/10.3348/kjr.2022.0651

Habib SS, Rafiq S, Zaidi SMA, Ferrand RA, Creswell J, Van Ginneken B, et al. Evaluation of computer-aided detection of tuberculosis on chest radiography among people with diabetes in Karachi, Pakistan. Sci Rep. 2020;10:6276. Available from: https://doi.org/10.1038/s41598-020-63084-7

Katende B, Bresser M, Kamele M, Chere L, Tlahali M, Erhardt RM, et al. Impact of a multi-disease integrated screening and diagnostic model for COVID-19, TB, and HIV in Lesotho. PLOS Glob Public Health. 2023;3(8):e0001488. Available from: https://doi.org/10.1371/journal.pgph.0001488

Klinkenberg E, Floyd S, Shanaube K, Mureithi L, Gachie T, de Haas P, et al.; TREATS study team. Tuberculosis prevalence after 4 years of population-wide systematic TB symptom screening and universal testing and treatment for HIV in the HPTN 071 (PopART) community-randomized trial in Zambia and South Africa: A cross-sectional survey (TREATS). PLoS Med. 2023;20(9):e1004278. Available from: https://doi.org/10.1371/journal.pmed.1004278

Qin ZZ, Barrett R, Del Mar Castro M, Zaidi S, Codlin AJ, Creswell J, et al. Early user experience and lessons learned using ultra-portable digital X-ray with computer-aided detection (DXR-CAD) products: A qualitative study from the perspective of healthcare providers. PLoS ONE. 2023;18:e0277843. Available from: https://doi.org/10.1371/journal.pone.0277843

Abdulloev NN, Rustamzoda ShD, Sattorov BA. Effectiveness of the implementation in the Republic of Tajikistan of a new innovative approach to the use of artificial intelligence for the interpretation of chest radiographs. In: Materials of the scientific and practical conference of the SEI ATSMU "New Horizons in Medical Science, Education, and Practice", with international participation. November 1, 2024;1:226.

Yang Y, Xia L, Liu P, Yang F, Wu Y, Pan H, et al. A prospective multicenter clinical research study validating the effectiveness and safety of a chest X-ray-based pulmonary tuberculosis screening software JF CXR-1 built on a convolutional neural network algorithm. Front Med (Lausanne). 2023;10:1195451. Available from: https://doi.org/10.3389/fmed.2023.1195451

Bobokhojaev OI, Rasulov EF, Abdurakhimov AA. Detection of pulmonary tuberculosis in the Republic of Tajikistan. Hospice & Palliative Medicine International Journal. 2024;7(3):96-98.

Bobokhojaev OI, Pulatova SJ, Saidova SN. Similarities in measures to prevent the spread of COVID-19 and tuberculosis. CME Journal of Clinical Case Report. 2024;1(1):1-3. Available from: https://www.wecmelive.com/open-access/similarities-in-measures-to-prevent-the-spread-of-covid19-and-tuberculosis.pdf

Pande T, Cohen C, Pai M, Ahmad Khan F. Computer-aided detection of pulmonary tuberculosis on digital chest radiographs: A systematic review. Int J Tuberc Lung Dis. 2016;20(9):1226-30. Available from: https://doi.org/10.5588/ijtld.15.0926

Santos AdS, de Oliveira RD, Lemos EF, Lima F, Cohen T, Cords O, et al. Yield, efficiency, and costs of mass screening algorithms for tuberculosis in Brazilian prisons. Clin Infect Dis. 2021;72(5):771-7. Available from: https://doi.org/10.1093/cid/ciaa135

Philipsen R, Sanchez C, Maduskar P, Melendez J, Peters-Bax L, Peter J, et al. Automated chest-radiography as a triage for Xpert testing in resource-constrained settings: A prospective study of diagnostic accuracy and costs. Sci Rep. 2015;5(1):12215. Available from: https://doi.org/10.1038/srep12215

MacPherson P, Webb EL, Kamchedzera W, Joekes E, Mjoli G, Lalloo DG, et al. Computer-aided X-ray screening for tuberculosis and HIV testing among adults with cough in Malawi (the PROSPECT study): A randomised trial and cost-effectiveness analysis. PLoS Med. 2021;18(9):e1003752. Available from: https://doi.org/10.1371/journal.pmed.1003752