Published: 09 May, 2025 | Volume 9 - Issue 1 | Pages: 014-022
Figure 1:
Mechanism of Action of Sotatercept in PAH. Sotatercept (blue) acts as a ligand trap, sequestering excess activin ligands (red) from binding to ActRIIA/B receptors, thereby rebalancing signaling toward BMP-mediated (green) antiproliferative pathways in pulmonary vascular cells.
Read Full Article HTML DOI: 10.29328/journal.jprr.1001068 Cite this Article Read Full Article PDF
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